Pharmaceutical Medicines

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Doripenem is a broad-spectrum carbapenem antibiotic used to treat a variety of serious bacterial infections. As a member of the beta-lactam class of antibiotics, Doripenem exerts its bactericidal effects by inhibiting bacterial cell wall synthesis. The 500mg dosage of Doripenem is typically administered intravenously (IV) to ensure rapid and effective delivery to the bloodstream, allowing it to act against infections in critical areas of the body, including the lungs, urinary tract, and abdomen.

Doripenem is highly effective against a wide range of gram-positive, gram-negative, and anaerobic bacteria, making it a key therapeutic option in treating complicated infections that are resistant to other antibiotics. The drug is commonly prescribed for complicated intra-abdominal infections (such as peritonitis or appendicitis), complicated urinary tract infections (including pyelonephritis), and hospital-acquired pneumonia, particularly in patients who are critically ill or have compromised immune systems.

The recommended dosage for adults typically includes an IV infusion of 500mg every 8 hours, although the exact dosing regimen may be adjusted based on the patient’s condition, kidney function, and response to therapy. In cases of severe infection or renal impairment, adjustments to the dose or infusion schedule may be necessary to ensure therapeutic efficacy while minimizing potential side effects.

Doripenem’s spectrum of activity includes many multidrug-resistant organisms, such as Pseudomonas aeruginosa, which makes it an important option for infections caused by resistant pathogens. Despite its broad spectrum, Doripenem is generally well-tolerated, with common side effects including nausea, headache, and mild gastrointestinal disturbances such as diarrhea. Serious side effects, though rare, may include allergic reactions or seizures, particularly in patients with a history of CNS disorders or renal impairment.

As with any antibiotic, it is essential to complete the full course of treatment with Doripenem to avoid the development of resistance. Misuse or overuse of antibiotics like Doripenem can contribute to the rise of antibiotic-resistant bacteria, making infections harder to treat in the future.

Overall, Doripenem 500mg is an effective and potent antibiotic option for treating a range of severe infections, especially those caused by resistant bacteria. Its careful use under the guidance of healthcare professionals ensures optimal outcomes and minimizes risks associated with antibiotic resistance and adverse effects.

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We are engaged in offering a wide range of  quality products  to our clients. Our range of all products is widely appreciated by our clients.

Approx. Rs 24.05 / PieceGet Latest Price

Product Details:

We are engaged in offering a wide range of  quality products  to our clients. Our range of all products is widely appreciated by our clients.

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The mechanism of action of Esomeprazole 40mg is based on its ability to inhibit the proton pump in the stomach lining. The proton pump is responsible for secreting hydrochloric acid (stomach acid) into the stomach. When Esomeprazole is ingested, it is absorbed into the bloodstream and transported to the parietal cells in the stomach. Here, it binds to the proton pump and inhibits its activity, leading to a significant reduction in acid production. This acid suppression helps alleviate symptoms like heartburn, regurgitation, and acid reflux, and it also allows healing of ulcers in the stomach or duodenum.

Uses of Esomeprazole 40mg

1. Gastroesophageal Reflux Disease (GERD): GERD is a chronic condition in which stomach acid frequently flows back into the esophagus, leading to symptoms such as heartburn, chest pain, and difficulty swallowing. Esomeprazole 40mg is often prescribed to control the acid reflux and prevent the associated damage to the esophageal lining.

2. Peptic Ulcers: Peptic ulcers, which include both gastric and duodenal ulcers, are sores that develop on the lining of the stomach or the upper part of the small intestine. These ulcers are often caused by an overproduction of stomach acid or by bacterial infections, such as Helicobacter pylori. Esomeprazole 40mg can help reduce the acid production and promote healing of these ulcers.

3. Zollinger-Ellison Syndrome: Zollinger-Ellison syndrome is a rare condition characterized by the overproduction of gastric acid due to tumors in the pancreas or duodenum. Esomeprazole 40mg helps control the excessive acid secretion, reducing the risk of complications such as ulcer formation and bleeding.

4. Prevention of Ulcers due to NSAID Use: Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and aspirin, can irritate the stomach lining and lead to ulcer formation. Esomeprazole 40mg is often used in combination with NSAIDs to reduce the risk of developing ulcers in people who require long-term use of these medications.

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Omeprazole 40MG inj.